marinabarrow
Marina Barrow • Joined a month ago
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marinabarrow/cardiacorganoidmodels
Ace Therapeutics’ new suite of model development services is designed to provide customized, reliable, and reproducible preclinical models that closely mimic various cardiovascular conditions. In addition to a variety of experimental animals including mice, rats, rabbits, and monkeys, Ace Therapeutics can assist worldwide clients in constructing custom animal models using techniques such as environmental enrichment, gene editing, dietary modifications, or drug therapies. Moreover, the company can also provide researchers with cardiac organoid models and human induced pluripotent stem cell (hiPSC) models to support their research into the mechanisms of cardiovascular disease and facilitate the development of effective new drugs and cell therapies. Ultimately, these diverse models are developed to bridge the gap between laboratory research and clinical application for most cardiovascular diseases such as atherosclerosis, hypertension, thrombosis, heart failure, and cardiovascular infection.
marinabarrow/type2diabetesmellitus
Ace Therapeutics provides diverse diabetic mouse models targeting type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM). The T1DM mouse models allow researchers to study the mechanism of type 1 diabetes, identify biomarkers, and test potential therapies. Mouse models for T2DM study is generated by feeding mice a high-fat or high-sugar diet or genetically modifying mice to develop obesity and insulin resistance. These models matter a lot in type 2 diabetes research. Different from T2DM mouse models, GDM mouse models involve feeding mice a high-fat or high-sugar diet during pregnancy or genetically modifying mice to develop impaired glucose tolerance and insulin resistance during pregnancy.