Microbial cell surface display technology holds great strategic potential for expressing heterologous proteins or polypeptides with a distinct function on the surface of microbial cells. To gain amenable cell surface exposure, the passenger protein could be fused with various anchoring motifs (carrier protein), which are usually cell-surface proteins or their fragments. Up to the characteristics of passenger and carrier proteins, this strategy can be carried out using different fusion methods, such as C-terminal fusion, N-terminal fusion or sandwich fusion. Creative Biogene provides various cell-surface display systems for the successful display of a target protein or peptide on the surface of bacteria via genetic fusion to anchoring motif. |
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