creativebioarray
Creative Bioarray • Joined a year ago
Top Projects
creativebioarray/3DCellCulture
Creative Bioarray can provide ready-to-use 3D cell cultures generated from various cell types. We have extensive experience in developing highly functional 3D cell culture models. Our scientific team can work with you to establish and optimize protocols, as well as design custom 3D cell culture models according to your specific requirements.
creativebioarray/3DCocultureModels
3D co-culture cell models now serve as important tools for solving scientific questions, which can be developed in different formats, depending on research goals and downstream usage. Co-culture cell models can emulate a variety of pathological conditions such as different stages of tumor invasion and metastasis, and identify of stromal components associated with pathological process.
creativebioarray/3DInvasionAssay
Invasion and metastasis are responsible for the high morbidity and mortality in cancer patients. Invasion into the surrounding normal tissues is generally considered to be a key hallmark of malignant tumors. More efforts for anticancer drug development now move towards therapies that targeted on the inhibition of this key "hallmark" of cancer. The 3D tumor spheroid invasion assay allows cells to invade out of the tumor mass into the extracellular matrix-like environment. The true 3D manner takes into account important aspects of the pathophysiology of a tumor mass, in which the tumor spheroids may experience hypoxia and nutrient deprivation which may cause the change in gene expression and promote migration and invasion. Creative Bioarray believes that the rapid, automatable 3D invasion system that enables highly reproducible experimental conditions and high throughput analysis will give our customers the best results to identify novel therapeutic agents.
creativebioarray/Adipocytes
Adipocytes are cells specialized in storing energy in the form of fat, mainly triglycerides, in organelles called lipid droplets. There are two major types of adipocytes in mammals: white adipocytes contain one large lipid droplet and are involved in fat storage, while brown adipocytes have many smaller lipid droplets and numerous mitochondria that generate energy, maintaining body temperature.
creativebioarray/ADME
Creative Bioarray offers comprehensive in vitro ADME services for drug discovery organizations. Many of our in vitro ADME assays come in a variety of formats to suit different stages of the drug discovery pipeline, enabling us to provide a flexible approach to our ADME services. While Creative Bioarray has standard procedures for each of these assays listed below, our experienced research team can also help design the best strategies and protocols customized to meet any drug discovery needs.
creativebioarray/BioanalyticalServices
Creative Bioarray develops and performs rapid, sensitive and robust bioanalytical methods for the extraction and quantitation of drugs and metabolites in biological fluids and tissues to support preclinical research. We provide cost-effective design and implementation of in vivo pharmacokinetic studies in various animal species and quick turnaround of results. Our bioanalytical capabilities serve every stage of your molecular development.